Sommario
Update on surfactant treatment in newborns, infants
and children
Index Surfactant
Importance of surface tension in lung mechanics
Surfactant: early history
Surfactant: early history
Surfactant: early history
Surfactant: first clinical trials
Surfactant review
Index Surfactant
Pulmonary surfactant functions
Pulmonary surfactant effects
Index Surfactant
Pulmonary surfactant composition
Surfactant proteins
Surfactant metabolism
Index Surfactant
Loss of surfactant function
Loss of surfactant function
Index Surfactant
Surfactant: types available
Dosing knowledge to date
Dosing indications
Proposed therapy based on lung injury stage at
the time of treatment
Surfactant delivery techniques
Surfactant delivery techniques
Distribution of supplemented surfactant in ARDS
Surfactant delivery techniques
Surfactant supplementation using selective intubation
Surfactant supplementation using selective intubation
Index Surfactant
Surfactant: major acute effects
Peak inspiratory pressure variations after surfactant
supplementation
Compliance variations after surfactant supplementation
Index Surfactant
Adverse effects of surfactant
Surfactant contraindication
Index Surfactant
Failure of surfactant therapy
Failure of surfactant therapy
Index Surfactant
Clinical trials and pilot studies on exogenous
surfactant supplementation
Clinical trials and pilot studies on exogenous
surfactant supplementation
Clinical trials and pilot studies on exogenous
surfactant supplementation
Clinical trials and pilot studies on exogenous
surfactant supplementation
pO2 / FiO2 ratio during ILV after surfactant supplementation
Compliance variations during ILV after surfactant
supplementation
Time before ILV-Surf (weeks) / ILV duration (hours)
/ Weaning time (days)
Clinical trials and pilot studies on exogenous
surfactant supplementation
Clinical trials and pilot studies on exogenous
surfactant supplementation
PaO2 / FiO2
PaCO2
Peak Inspiratory Pressure
Clinical trials and pilot studies on exogenous
surfactant supplementation
Clinical trials and pilot studies on exogenous
surfactant supplementation
PaO2 / FiO2
PaCO2
Peak Inspiratory Pressure
Duration of CPPV and ICU stay
Clinical trials and pilot studies on exogenous
surfactant supplementation
Normal Lung
ARDS
Sepsis-induced ARDS
Sepsis-induced ARDS
Surfactant supplementation in ARDS
ARDS in oncohematologic children
Surfactant supplementation in ARDS Before treatment
Surfactant supplementation in ARDS After treatment
PaCO2
Clinical trials and pilot studies on exogenous
surfactant supplementation
Remain unsolved
Surfactant lines the alveolar surface and
Picu image
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