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An antinfective effect, principally towards group B Streptococcus, has been observed both in vitro and in vivo. An antiviral effect has also been described. Such effects are most likely connected to SP-A.
Sherman MP, Campbell LA, Merritt TA, Long WA, Gunkel JH, Curstedt T, Robertson B. Effect of different surfactant on pulmonary group B streptococcal infection in premature rabbits. J Pediatr 1994; 125:939-947
Herting E, Jarstrand C, Rasool O, Curstedt T, Sun B, Robertson B. Pediatr Res 1994
Le Vine AM, Bruno MD, Huelsman KM, Ross GF, Whitsett JA, Korfhagen T. J. Immunol 1997
Herting E, Gefeller O, Land M, van Sonderen L, Harms K, Robertson B and Members of the Collaborative European Multicenter Study Group. Pediatrics 2000